Umicore CX84

Umicore CX84

Dichlorobis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium(II)

CAS Number: 887919-35-9

Product class: M-P, Homogeneous Catalysts, Monodentate Ligands, Phosphorus Ligands - Achiral

Reaction type: Cross Coupling Reactions with Arenes, Suzuki-Miyaura Coupling Reaction

Chemical properties

Chemical formula

C32H56N2Cl2P2Pd

Empirical formula

[Pd(amphos)2Cl2]

Molecular weight

708.08

Metal

Pd

Theoretical metal content

15

Physical state

powder

Color

yellow

Metal purity

99.95

Applications & references

Synthesis of the pyrazolopyridinone-based p38 mitogen-activated protein kinase inhibitor including a Suzuki coupling reaction. p38 MAP kinases are intercellular serine/threonine kinases which certainly regulate the production and action of several pro-inflammatory mediators. They are also involved in disease states such as rheumatoid arthritis, Crohn’s diseases and psoriasis.

Reference: Org. Proc. Res. Dev. 2011, 15, 31. (DOI: 10.1021/op100205s)

Request a quote or MSDS

Get in touch
×

      Umicore uses certain monitoring and tracking technologies such as cookies. These technologies are used in order to maintain, provide and improve our services on an ongoing basis, and in order to provide our web visitors with a better experience.

      By clicking on the "Accept all" button you agree to the use of these cookies while using the website. For further information regarding how we use cookies and other tracking technologies, please see section 11 of our website privacy notice. 

          Necessary cookies are essential and help you navigate our website. This helps to support security and basic functionality and are necessary for the proper operation of our website, so if you block these cookies we cannot guarantee your use or the security during your visit.

          Cookies that help us to understand the behaviour of users of our website. This allows us to continuously improve our website to provide the best information in support of our project aims. These cookies also help us understand the effectiveness of our website. For instance these cookies tell us which pages visitors go to most often and if they get error messages from web pages.

          Cookies that deliver content to you based on your interests, which are assumed from your browsing history. Most Targeting Cookies track users via their IP address and, thus, may collect some Personal Data. Personal Data collected by Targeting Cookies may be shared with third parties, such as advertisers.