CAS Number: 905459-27-0
Product class: M-P, Homogeneous Catalysts, M-N, N-Heterocyclic Carbene Ligands, M-C, IPr, PEPPSI Ligands, Pyridyl Ligands, Bidentate Ligands
Reaction type: Cross Coupling Reactions with Arenes, Amination, Buchwald-Hartwig Aminaton, CH-Activation, Kumada Coupling Reaction, Negishi Coupling Reaction, Oxidation, Sonogashira-Hagihara Coupling Reaction, Suzuki-Miyaura Coupling Reaction
US 6 316 380, WO 2004 014550 and foreign equivalents apply. Quantities up to 1kg are exclusively sold by Sigma Aldrich Catalogue.
Applications & references
Preparation of substituted heterobicyclic carboxylic acids, as well N-oxides and agriculturally accepted salts, which are applied in controlling plant growth.
Manufacture of pyrazol derivatives as modulators of cannabinoid receptors, which are useful in the treatment of obesity and overweight.
Reference: WO2008 074982
Novel synthetic approach of glycine transport GT1 inhibitor sacrosine.
Reference: WO2007 060203
Intramolecular direct arylation of aryl chlorides.
Reference: Synth. Comm. 2011, 41, 41 (DOI: 10.1080/00397910903531755)
Oxidation of secondary alcohols.
Reference: J. Org. Chem. 2011, 76, 1390 (DOI: DOI: 10.1021/jo102385u)
Suzuki-Miyaura coupling reaction.
Reference: Org. Lett. 2011, 13, 146 (DOI: 10.1021/ol1027283)
Negishi coupling reactions.
Reference: Chem. Eur. J. 2006, 12, 4749 (DOI: 10.1002/chem.20060020) ; Org. Lett. 1999, 1, 1323 (DOI: 10.1021/ol9907872); J. Org. Chem. 2002, 67, 79 (DOI: 10.1021/jo0105787)
Palladium catalyzed anaerobic oxidation of secondary alcohols under mild reaction conditions.
Reference: J. Org. Chem. 2011, 76, 1390 (DOI: 10.1021/jo102385u)